EBOV is believed to infect humans by means of contact with mucous membranes or pores and skin breaks.[fifty four] following infection, endothelial cells (cells lining the inside of blood vessels), liver cells, and a number of other varieties of immune cells which include macrophages, monocytes, and dendritic cells are the most crucial targets of assault.[54] pursuing an infection, immune cells have the virus to close by lymph nodes in which more replica on the virus usually takes put.
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[83] Though some canines in an area through which a human outbreak occurred had antibodies to EBOV, it really is unclear whether they played a role in spreading the sickness to people today.[83] Reservoir
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