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[fifty one] Once interferon has certain to its receptors to the neighbouring cell, the signalling proteins STAT1 and STAT2 are activated and shift for the cell's nucleus.[fifty one] This triggers the expression of interferon-stimulated genes, which code for proteins with antiviral properties.[fifty one] EBOV's V24 protein blocks the manufacture of these antiviral proteins by preventing the STAT1 signalling protein in the neighbouring cell from getting into the nucleus.[51] The VP35 protein instantly inhibits the manufacture of interferon-beta.[95] By inhibiting these immune responses, EBOV may perhaps speedily spread throughout the system.[49] analysis

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